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Young Kwang Chae 1, Taeyeong Ko 1, Sangmin Chang 1, Jonathan Anker 1, Sarita Agte 2, Wade Iams 1, Marcelo Cruz 1 1 Northwestern University Feinberg School of Medicine, Chicago, IL, USA 2Robert H.

Higgs 1, Koustubh Ranade 1 1 MedImmune, Gaithersburg, MD, USA Adoptive immunotherapy Bioinformatics Chemotherapy Tumor microenvironment Checkpoint blockade Clinical study Antibody Gene expression Solid tumors.

Erbe 1, Wei Wang 1, Lakeesha Carmichael 1, Anna Hoefges 1, KyungMann Kim 1, Wendy B.

Blokhin Russian Oncology Research Center, Moscow, Russian Federation 2The Central Clinical Hospital for Presidential Affairs, Moscow, Russian Federation 3The Moscow City Oncology Hospital No.

, Redwood City, CA, USA 2Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA T cell lineages Immune monitoring Biomarkers Antibody B cell T cell Tumor infiltrating lymphocytes TILs P103 Tumor infiltrating lymphocyte TIL percentage as a prognostic biomarker for overall and relapse free survival in Hu14.

18K322A are associated with outcome in a phase I trial of hu14.

Kaufmann 1, Judy Jacques 1, Christine McCoy 1, Michael O'Keeffe 1, Crystal Cabral 1, Yana Ostrovsky 1, Ning Wu 1, Jason Dobston 1, Theresa Zhang 1, Pamela Carroll 1, Jessica Flechtner 1, Wendy Broom 1 1 Genocea Biosciences, Inc.

, New Haven, CT, USA 2Alexion Pharmaceuticals, Inc.

, Kenilworth, NJ, USA 10University of California, San Francisco, San Francisco, CA, USA Antibody Biomarkers Checkpoint blockade Clinical trial Clinical study Gene expression Solid tumors Targeted therapy T cell Tumor microenvironment P80 Testing Systems Immune Monitoring by Mass Cytometry for Clinical Correlative Research Caroline Roe 1, Allison Greenplate 1, Jonathan Irish 1 1 Vanderbilt University, Nashville, TN, USA Systems biology T cell Immune monitoring Biomarkers Checkpoint blockade Targeted therapy P81 The immunomodulatory effects of cancer therapy on IFN-gamma responses in the periphery Laura Rosa Brunet 1, James Crooks 2, Andrew MacDonald 2, Samuel LaBrie 3, Dominic Eisinger 3 1 Immodulon Therapeutics Ltd, Uxbridge, United Kingdom 2Manchester University, Manchester, United Kingdom 3Myriad RBM, Austin, TX, USA Biomarkers Immune monitoring Immune adjuvant Dendritic cell T cell P82 Potential biomarkers in mRCC patients treated with nivolumab Maria Sayapina 1, Dmitry Nosov 2, Nikita Savelov 3, Nina Lyubimova 1, Yuriy Timofeev 1 1 N.

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Congregational Contact — Alma Westlake• Meyers 7, Peter Ordentlich 5, Sanjiv S.