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Admin30.06.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Malignant pleural mesothelioma: clinicopathologic and survival characteristics in a consecutive series of 394 patients.
8001
Admin20.07.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Mairinger FD, Werner R, Flom E, Schmeller J, Borchert S, Wessolly M, et al.
7001
Admin16.08.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Enhanced base excision repair, due to defective HRR that is caused by BRCAness phenotype, increases the reliance on PARP1.
1909
Admin08.08.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

7 Ruhrlandklinik, West German Lung Centre, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
7109
Admin03.09.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

The present data can lead to a better understanding of the underlaying cellular mechanisms and leave the door wide open for new therapeutic approaches for this severe disease with infaust prognosis.
206
Admin12.07.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

The gene expression pattern identified could be found in approx.
1408
Admin11.06.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Furthermore, we aimed to find possible correlations between response and gene expression patterns associated with BRCAness phenotype.
3000
Admin29.07.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

9 Department of Pathology, Diakonissenkrankenhaus Flensburg, Flensburg, Germany.
Admin30.07.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

8 Department of Thoracic Surgery and Thoracic Endoscopy, Ruhrlandklinik, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
58010
Admin21.06.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Comparison of SKIP expression in malignant pleural mesotheliomas with Ki-67 proliferation index and prognostic parameters.
3904
Admin13.06.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

An inhibition of this pathway with olaparib might abrogate this effect and induce apoptosis.
4304
Admin01.07.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Borasio P, Berruti A, Bille A, Lausi P, Levra MG, Giardino R, et al.
3900